It depends on which firmware you upgraded from. If you upgraded from 2.2.1 (i.e. 2.2.1(0) ) to 2.2.1(1), it won’t trigger a factory reset, all settings, programs, including WiFi settings are preserved, there is no need to re-configure WiFi.
If you upgraded from 2.2.0 or earlier to 2.2.1(1), then it will trigger a factory reset and you need to re-configure WiFi.
The easiest way to tell is to look at the LCD screen — does it show 4 lines with a blinking dot? If so, it’s in AP mode, and the OS_xxxxxx SSID will be printed onto the LCD screen. If not, that means it didn’t trigger factory reset, and it should connect to your WiFi router already.