I would think so, although you might have to do some work in the OS to get the GPIO pins mapped into use. For example, in Dan’s python-based Interval program you might need to map in a new python library to access the GPIO pins. Since the OSPi is all controlled from the GPIO pins that’s really all you need to do.
I think the OSPi can even power the HummingBoard, but I don’t know that for sure. It looked like it from the quick look I took at the hardware definition but Ray should confirm that. Otherwise, you might have to use an external power source.